A Look at Cannabidiol, or CBD for Anxiety

(3-5 min read)

In my introductory post here on Herbswift last month, I shared my perspective on the public health risks of legal CBD, and my concerns about inconsistent product quality (low CBD or high THC), lack of clear labeling or non-existent standardized, industry dosing.

In this installment, I promised to address Anxiety because I get more questions regarding the treatment of chronic Anxiety with CBD, than any other question. My intention here is to give readers a place to start when considering CBD for Anxiety.

A Look at Cannabidiol, or CBD for Anxiety.

Chronic Anxiety seems to be the most frequent clinical problem for people age 25 to 45, who are seeking CBD as a potential treatment option. It certainly is the most frequent condition I get asked about from women.

In anxiety, CBD can help multiple symptoms including:

generalized anxiety

panic attacks

compulsive behaviors

long-term effects of stress.

In fact, the endocannabinoid system is critical in regulating mood and protecting us from extreme anxiety. And though CBD does not bind directly to cannabinoid receptors in the body, it does bind directly to serotonin receptors in the midbrain.

The 5-HT1A receptors CBD activates in the midbrain, are the very same receptors targeted by conventional anti-anxiety medications like Buspar and Paxil. Yet according to the evidence, it seems CBD works much faster than traditional anti anxiety meds and with less longterm risks.

Studies in humans using 99% pure, CBD isolate have demonstrated that CBD is a safe and well tolerated compound when delivered acutely by oral, inhalation or intravenous routes.

Additionally, researchers found that administration of CBD in oral daily dosing ranging from 10mg – 1280mg, in healthy volunteers, patients with Schizophrenia, Bipolar affective disorder and Parkinson’s disease, among other conditions, did not experience any adverse side effects.

A dosing range of 5mg – 10mg/kg, of pure CBD, produced the best range of positive effects, in Anxiety, while, high doses, over 600mg/day, became ineffective. This reflects the biphasic nature and dosing curve of CBD, common to both animal and human studies, which demonstrate an optimal therapeutic window for the effectiveness of CBD in any given condition.

In Anxiety, 300mg and 400mg of 99%, pure CBD isolate provided the greatest relief on tests for Social Anxiety in public speaking, while doses of 100mg and 600mg, were ineffective.

What does this mean for anyone wanting to try CBD for Anxiety?

First, consumers need to understand it took high doses of 300 to 400 mg of CBD to reduce Social Anxiety in the research, therefore it may require a significant amount of CBD to get the same results in real life.

Second, its important for consumers to understand that although we talk about the benefits of whole plant and full spectrum CBD, all research done on CBD, in the last 30 years, has been done with purified CBD isolate. Unless treating with pure, 99% CBD, results will be different.

Finally, its important to experiment with CBD to find your own optimal dosing range, as well as a cost-effective CBD product, to ensure you can afford the treatment costs of CBD.

Well I hope this helps your understanding of how CBD works for anxiety and what doses work best according to the research evidence. Until next time, enjoy your CBD experience and come back in a couple of weeks for my next installment here at Herbswift.

Remember to smile, its the best way to activate endocannbinoids “on demand” and bring a little euphoria into your life at any moment in time.

Blog-Rocks (1)

CBD – Let’s start with the basics!

(3-5 min read)


The historic signing of the Farm Bill, 2018 ushered in a new era for industrial Hemp based products with an expected $2.1 billion market in consumer sales by 2020. According to market research published by the Hemp Business Journal; $90 million will come solely from hemp based CBD, or Cannabidiol.

Consumers are now facing a dizzying array of choices in industrial hemp based CBD products sold online, in retail shops and in some cities, even at the local juice bar and coffee shop.

The Public Health Impact of Legal CBD

The explosion of CBD products is a long awaited development in the effort to free cannabis as an industrial crop by allowing greater legal access to hemp derived products for the mainstream public.

However, consumers will also be at increased public health and safety risk as more people try CBD, is currently without any standardized dosing or product labeling regulations. 

How are consumers to determine optimal dietary supplementation with such a wide variety of product choices and such conflicting information available in the mainstream?

Even worse, what happens if someone taking a legal hemp CBD product fails a random employee drug test? Who’s responsible if a consumer loses a job from taking a product with too much THC, the illegal cannabis molecule?

Let the buyer beware, as I have seen it happen.

A Little Background Story

My name is Courtney Allen-Gentry, RN MSN PHN AHN-BC HWNC-BC and I am a Board Certified Advanced Holistic Nurse Coach and Public Health Nurse. One of only 28 nurses in the country with these holistic board certifications; I am the only nurse specializing in cannabis integration in public health. 

My mission is educating the public and raising awareness about Cannabis, CBD, Marijuana and Hemp. My goal is to ensure every person understands enough about these terms to make informed choices.

Additionally, I’m a Holistic Nurse Coach Preceptor, a Nurse Scholar, Researcher and Public Speaker. I have presented my work on cannabis education at academic conferences around the world and am currently working on the determination of subtle universal frequencies by our endocannabinoid system. More on that later.

My job here on Herbswift, is to walk you through everything you need to know in order to be your own CBD, Hemp or Cannabis expert.

And after reading my little guide, my intention is for you to feel much more comfortable talking about Hemp, legal CBD, Marijuana or cannabis overall. In fact understanding what these terms mean are the key to understanding everything in the landscape of cannabis and hemp derived CBD.

Lets just start with the basics here and work our way into a greater knowledge base over the coming weeks. I’ll make sure you know enough to feel comfortable making choices about CBD, and perhaps even a little holistic self care thrown in to boot.

The Basics 

Although CBD is only one of over 120 or more plant molecules called ‘cannabinoids” identified in the Cannabis plant, everyone is talking about CBD because of its popularity with the Epilepsy Moms who worked tirelessly on the legalization of CBD across the Country and all over the World. In fact, if it were not for the efforts of these Mothers, I’m certain we would not have legalization at this very moment.

Cannabidiol, CBD does not activate cannabinoid receptors, but moderately inhibits the breakdown of the our own molecules of bliss; molecules like THC in the cannabis plant which help us feel happy. Termed “the molecule of bliss” Anandamide is part of the basic endocannabinoid system.

A whole system you say? Yes, the Endocannabinoid System consisting of receptors CB1 and CB2 and their molecule keys, Anandamide and 2-AG and a few other enzymes that breakdown or make cannabinoids.

The Endocannabinoid system, ECS, regulates:

energy flow and production

immune function

development of the baby inside the Uterus

suckling and nursing



memory extinction

immune function to name just a few.

Every time you think a new thought, acquire new knowledge, feel pain relief, recover from an injury, have a restful sleep and forget the bad stuff, the endocannabinoid system is involved. Indeed it is the master regulator of homeostasis; responsible for balancing and harmonizing every level of existence, mind body and Spirit.

When asked about the main purpose of the endocannabinoid system Dr. Vincinzo DiMarzo, the most prolific cannabis researcher in the world, summed it up as “relax, eat, sleep, protect and forget”.

For The Next Installment

We will talk about some of the things CBD helps like Sleep and Anxiety to start with. Hope you enjoyed this little intro and will come back and join me for more on CBD and the endocannabinoid system.