(3-5 min read)
In my introductory post here on Herbswift last month, I shared my perspective on the public health risks of legal CBD, and my concerns about inconsistent product quality (low CBD or high THC), lack of clear labeling or non-existent standardized, industry dosing.
In this installment, I promised to address Anxiety because I get more questions regarding the treatment of chronic Anxiety with CBD, than any other question. My intention here is to give readers a place to start when considering CBD for Anxiety.
A Look at Cannabidiol, or CBD for Anxiety.
Chronic Anxiety seems to be the most frequent clinical problem for people age 25 to 45, who are seeking CBD as a potential treatment option. It certainly is the most frequent condition I get asked about from women.
In anxiety, CBD can help multiple symptoms including:
long-term effects of stress.
In fact, the endocannabinoid system is critical in regulating mood and protecting us from extreme anxiety. And though CBD does not bind directly to cannabinoid receptors in the body, it does bind directly to serotonin receptors in the midbrain.
The 5-HT1A receptors CBD activates in the midbrain, are the very same receptors targeted by conventional anti-anxiety medications like Buspar and Paxil. Yet according to the evidence, it seems CBD works much faster than traditional anti anxiety meds and with less longterm risks.
Studies in humans using 99% pure, CBD isolate have demonstrated that CBD is a safe and well tolerated compound when delivered acutely by oral, inhalation or intravenous routes.
Additionally, researchers found that administration of CBD in oral daily dosing ranging from 10mg – 1280mg, in healthy volunteers, patients with Schizophrenia, Bipolar affective disorder and Parkinson’s disease, among other conditions, did not experience any adverse side effects.
A dosing range of 5mg – 10mg/kg, of pure CBD, produced the best range of positive effects, in Anxiety, while, high doses, over 600mg/day, became ineffective. This reflects the biphasic nature and dosing curve of CBD, common to both animal and human studies, which demonstrate an optimal therapeutic window for the effectiveness of CBD in any given condition.
In Anxiety, 300mg and 400mg of 99%, pure CBD isolate provided the greatest relief on tests for Social Anxiety in public speaking, while doses of 100mg and 600mg, were ineffective.
What does this mean for anyone wanting to try CBD for Anxiety?
First, consumers need to understand it took high doses of 300 to 400 mg of CBD to reduce Social Anxiety in the research, therefore it may require a significant amount of CBD to get the same results in real life.
Second, its important for consumers to understand that although we talk about the benefits of whole plant and full spectrum CBD, all research done on CBD, in the last 30 years, has been done with purified CBD isolate. Unless treating with pure, 99% CBD, results will be different.
Finally, its important to experiment with CBD to find your own optimal dosing range, as well as a cost-effective CBD product, to ensure you can afford the treatment costs of CBD.
Well I hope this helps your understanding of how CBD works for anxiety and what doses work best according to the research evidence. Until next time, enjoy your CBD experience and come back in a couple of weeks for my next installment here at Herbswift.
Remember to smile, its the best way to activate endocannbinoids “on demand” and bring a little euphoria into your life at any moment in time.